منابع مشابه
Zinc Exploitation by Pathogenic Fungi
The ability of pathogenic microorganisms to assimilate nutrients from their host environment is one of the most fundamental aspects of infection. To counteract this, hosts attempt to withhold essential micro-nutrients from potentially harmful microbes to limit, or even prevent, their growth. This process is called nutritional immunity. For example, vertebrates, such as humans, express several i...
متن کاملThe Zinc Transport Systems and Their Regulation in Pathogenic Fungi
Zinc is an essential micronutrient required for many enzymes that play essential roles in a cell. It was estimated that approximately 3% of the total cellular proteins are required for zinc for their functions. Zinc has long been considered as one of the key players in host-pathogen interactions. The host sequesters intracellular zinc by utilizing multiple cellular zinc importers and exporters ...
متن کاملFever from pathogenic fungi.
Most studies of fever have dealt with the pyrogenic activity of the bacterial lipopolysaccharides of gram-negative bacteria (1). The pyrogenic properties of pathogenic gram-positive bacteria, on the other hand, have been the stubject of only a few reports. It is of interest, however, that intravenous injection of living staphylococci and corynebacteria were found to produce higher fever in rabb...
متن کاملInsertional mutagenesis of pathogenic fungi.
Screening insertional mutants for loss of virulence is an effective method for investigating the molecular genetic basis of bacterial pathogenesis, but has only recently been applied to fungal pathogens. For many pathogenic fungi transformation with heterologous plasmid DNA results in complex integration events. This problem can now be circumvented for some species using restriction enzyme medi...
متن کاملAntifungal resistance in pathogenic fungi.
Pathogenic fungi are the cause of life-threatening infections in an increasing number of immunocompromised patients. The intrinsic resistance to antifungal therapy observed in some genera, along with the development of resistance during treatment in others, is becoming a major problem in the management of these diseases. We reviewed the epidemiology of the most common systemic fungal infections...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2012
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1003034